Isadore Weiner, painter, printmaker and teacher, was born in Chicago, Illinois in 1910. He studied at the School of the Art Institute of Chicago and taught at Hull House in Chicago. He shared a studio on Chicago’s South Side with artists Eleanor Coen, Max Kahn, and Misch Kohn. This group of artists pioneered color lithography as it wasn't supported by the faculty of the School of the Art Institute of Chicago. About 1935, Weiner joined the rolls of the WPA and worked in the Illinois graphics program in Chicago. Weiner's art was included in the Annual Exhibition of Artists of Chicago and Vicinity in 1939, 1940 and 1941.

Isadore Weiner’s work is represented in the collections of the Baltimore Museum of Art, Maryland; the Art Institute of Chicago, Illinois; the Metropolitan Museum of Art, New York; the Philadelphia Museum of Art, Pennsylvania; the Illinois State Museum, Springfield; the Krannert Art Museum, University of Illinois, Urbana-Champaign; the National Gallery of Art and the Smithsonian American Art Museum, Washington, D.C.; and the United States Government Collection of WPA works.

According to the research of Peter Falk, Isadore Weiner died around 1940/'41.

[There has been much speculation that Weiner died in Los Angeles in 1964, but a search of the Social Security Death Records clearly indicates that the 1964 date refers to the death of a different Isadore Weiner.]