Claude Weisbuch was born on February 8, 1927 in Thionville, France. Weisbuch studied at the Beaux-arts de Nancy. He had his first solo exhibition in 1957 in France, and went on to show in the United States and Japan. As a theatre and classical music enthusiast, the artist had a flair for what is raw, ecstatic, and controlled. He began teaching engraving at the school of Fine Arts of Saint-Etienne. With little acknowledgement at the beginning of his career it wasn't until 1961 that he started to become successful when he received the annual prize from the critics. He became most noted for his graphic works, especially engraving.

“I like the sketch, the uncompleted, the painting filled with mystery,” the artist has said. Weisbuch’s works are in the collections of the Centre Georges Pompidou in Paris, the Stedelijk Museum in Amsterdam, The Museum of Modern Art in New York, and the Staaliche Graphische Sammlung in Munich, among others. His subject matter has been compared with that of Toulouse-Lautrec, dancers, circus figures, horses, musicians, etc. all caught in a swirl of activity. It has been said that "Claude Weisbush ceaselessly captures life's dynamics, as would an instant cliché, the pictorial, musical and literary expressions that are essentially human."

Claude Weisbuch died on April 13, 2014 in Paris, France.

His work is found in the collections of: Musée cantonal des Beaux-Arts, Lausanne; Muséo Provencial de Bellas Artes, Cordoba; Muzej Savremene Umenosti, Belgrad; Bibliothèque Nationale, Paris; Centre National D'Art Contemporain, Paris; Muzeum Sztoki w Lodzi, Lodz; The Art Gallery of South Australia, Adélaide; Muzeum Narodowe, Warszaw; Musée d'Art Moderne de la ville de Paris; Muzeum Narodow, Krakow; Muzej na Sovremana Umetnost, Skopje; The MOMA , New York; Centre Beaubourg, Paris; Stedelijk museum, Amsterdam; Staadtlische Graphische Sammlung, Munich;  Staatsgalerie, Stuttgart; Göteborgs Keinstmuseum, Göteborg; Musée de Rennes; Cabinet des Estampes, Strasboug; Musée de Mulhouse, and Académie royale, Bruxelles.